I have still played relatively few first person shooters using the Wii remote, which is surprising when you consider how well it works. It's easy to aim at an enemy quickly, and as long as you fiddle with the sensitivity settings it can be much quicker to turn than a pad.
I enjoyed my time playing The Conduit's multiplayer, although I was hopeless. I'm pretty sure that a couple of the games I played were ruined by hackers - people who came into a room, survived a few headshots, and killed me with one shot. If they're not good enough to play properly, so be it.